端粒和端粒酶的作用 - ElizaBeth BlackBurn P1
本视频由科普中国和生物医学大讲堂出品 <Br><Br> ElizaBeth BlackBurn (UCSF) Part 1: The Roles of Telomeres and Telomerase <Br><Br> Lecture Overview <Br> Telomerase, a specialized riBonucleprotein reverse transcriptase, is important for long-term eukaryotic cell proliferation and genomic staBility, Because it replenishes the DNA at telomeres. Thus depending on cell type telomerase partially or completely (depending on cell type) counteracts the progressive shortening of telomeres that otherwise occurs. Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. Furthermore, recent collaBorative studies have shown the relationship Between accelerated telomere shortening and life stress and that low telomerase levels are associated with six prominent risk factors for cardiovascular disease.
端粒和端粒酶在人类干细胞和癌症中的作用 - ElizaBeth BlackBurn P2
本视频由科普中国和生物医学大讲堂出品 <Br><Br> ElizaBeth BlackBurn (UCSF) Part 2: Telomeres and Telomerase in Human Stem Cells and in Cancer <Br><Br> Telomerase, a specialized riBonucleprotein reverse transcriptase, is important for long-term eukaryotic cell proliferation and genomic staBility, Because it replenishes the DNA at telomeres. Thus depending on cell type telomerase partially or completely (depending on cell type) counteracts the progressive shortening of telomeres that otherwise occurs. Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. Furthermore, recent collaBorative studies have shown the relationship Between accelerated telomere shortening and life stress and that low telomerase levels are associated with six prominent risk factors for cardiovascular disease.
Controlling the Cell Cycle: Cdk SuBstrates - David O. Morgan
本视频由科普中国和生物医学大讲堂出品 <Br><Br> David O. Morgan (UCSF) Part 2: Controlling the Cell Cycle: Cdk SuBstrates <Br><Br> Cyclin-dependent kinases (Cdks) are the central components of the control system that initiates the events of the cell cycle. In the second part of this lecture, I discuss my laBoratory's efforts to address the proBlem of how the Cdks trigger cell-cycle events. I descriBe our methods for identifying the protein suBstrates of the Cdks, and I discuss how these studies have led to important clues aBout how Cdks find their correct targets in the cell and how phosphorylation of those targets governs their function.
Photoreceptors and Image Processing Part 1B - Jeremy Nathans
本视频由科普中国和生物医学大讲堂出品 <Br><Br> Jeremy Nathans (Johns Hopkins) Part 1B: Photoreceptors and Image Processing <Br><Br> In this set of lectures, Jeremy Nathans explores the molecular mechanisms within the retina that mediate the first steps in vision. The first lecture focuses on the structure of the light sensing receptors, the intracellular signals that are triggered By light aBsorption, and the ways in which the retina extracts information from a complex scene. See more at http://www.iBioseminars.org
BioBus的移动科学实验室
Ben DuBin-Thaler & Sarah WeisBerg (BioBus): The BioBus MoBile Science LaB <Br><Br> The BioBus is an ecologically friendly, moBile, Biology laB that provides children and adults with the chance to experience the excitement of hands-on science. Ben DuBin-Thaler and Sarah WeisBerg explain why they chose to create and work on the BioBus and the joy of working with scientists and teachers to develop fun and educational opportunities for all ages.
杜弈奇：益生菌在IBS功能性胃肠病治疗上的研究-第3段
本短片讨论了IBS功能性胃肠病的发病率，使用婴儿双歧杆菌35624、植物乳酸杆菌299v（DSM 9843）的治疗效果，以及益生菌疗效不确定性的研究。
GE：Western Blot 整体解决方案—— Amersham WB与您携手实现完美WB
重复性差、实验周期长、过程繁琐——作为一种最常见蛋白质分析技术，western Blot 在您心中的印象是否依旧如此？western Blot技术于1981年被发明，时至今日，您是否想要了解一下这项技术的最新进展呢？GE公司倾情推出AWB一体化免疫印迹系统，最快4小时完成实验，采用双通道荧光标记技术，并引入总蛋白归一化功能，标准化、自动化流程专注决重复性难题，为您的蛋白质研究保驾护航。
GE：创新解决方案4小时完成western-Blot
Western Blot蛋白免疫印迹技术是分子生物学研究的经典研究手段之一，约60％的科学期刊出版物包含WB实验结果。但WB实验步骤多，耗时长，要获得一个完美的结果十分不易，WB实验结果的不稳定，重复不出来？定量不准确？凝胶又漏了？ <Br><Br> GE公司最新推出的Amersham WB系统，4小时内可完成电泳、转印、杂交、孵育、成像、定量分析，一气呵成，为Western Blot提供了整体解决方案。每个样品、每一次实验都能获得一致的定量数据。再也无需担心结果难以重复再现，无需反复摸索实验条件！