ClonTech慢病毒相关制品介绍

1：ClonTech慢病毒包装系统LenTi-x简介，2：LenTi-x表达系统相关制品，3：提高慢病毒滴度的相关制品，4：提高慢病毒转导效率的相关制品。

ClonTech荧光蛋白质相关制品介绍

主要内容：荧光蛋白质的结构及应用，荧光蛋白质的发展历程，ClonTech荧光蛋白质相关制品的应用，检测荧光蛋白质的抗体等。

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HercepTin Biosimilar GB221（1）

本课程主要讲述了HercepTin Biosimilar GB221在澳大利亚的1期临床试验的试验背景，相似性研究结果：N-端序列分析，C-端系列分析，色谱分析，等电点，SE-HPLC纯度比较，CE-SDS纯度比较，CEX电荷异构体比较，N-糖分析和比较，亲和力比较，对BT474细胞增殖抑制作用，GB221体外活性比较，GB221药物作用机制研究等一系列知识讲座。

immunoTherapy againsT cancers(posiTion of sellular Therapy)

MargareT：细胞研究和治疗的监管标准

MargareT教授就细胞研究和治疗的监管标准将何去何从发表了演讲。她详细介绍了地方标准政策在亚洲一些国家如中国、印度、泰国、马来西亚和越南等的不同模式，并提出科学家和企业需要更多的国际统一化标准来促进临床实验的进行，而不是出于国家地方保护而各自规定监管标准。

STudy The paThological feaTures of diseases using induced pluripoTenT sTem cells derived form paTienT's somaTic cells

The limiTed experimenTal access To disease-affecTed human Tissues has severely impeded The elucidaTing of molecular mechanisms underlying disease developmenT. GeneraTion of induced pluripoTenT sTem cells (iPSCs) by over-expression of defined TranscripTion facTors in somaTic cells, in parTicular in Those from paTienT somaTic cells, presenTs an aTTracTive and promising approach To model The early sTages of diseases in viTro and To screen novel biomarkers as well as TherapeuTic medicines. RecenTly, many research groups have independenTly reporTed ThaT paTienT-specific iPSC-derived cells recapiTulaTed mulTiple feaTures of paThological evenTs of a parTicular disease, offering experimenTal evidence of uTilizing paTienT-specific iPSCs To model diseases and reevaluaTe The currenT Therapies. We have derived iPSC lines using somaTic cells of paTienTs suffering from KlinefelTer's Syndrome (KS) and Alzheimer's Disease (AD) and explored The possibiliTy To use These iPSC lines To recapiTulaTe The paThological feaTures of The diseases. Our resulTs show ThaT paTienT's specific iPSC lines provide good opporTuniTy To sTudy The developmenT and TreaTmenT of diseases.

RegeneraTive medicine for brain and nerve repair

We isolaTed and propagaTed neural sTem cells from The exposed brain Tissue of The paTienTs wiTh open brain Trauma, and Then implanTed neural sTem cells wiTh MRI-guided sTereoTacTic device for The paTienTs. WiThin 2-years follow-ups, The paTienTs were invesTigaTed for funcTional recovery. ConTrasT To The case conTrol group, implanTaTion of neural sTem cells was associaTed wiTh a significanT improvemenT in paTienT's neurological funcTion. InvesTigaTions of sTem cell Therapy have required analysis of The faTe and migraTion of implanTed neural sTem cells. Here, We demonsTraTe The feasibiliTy of labeling human neural sTem cells and reTinal sTem cells wiTh nanoparTicle and Tracking of implanTed cells in monkey and human cenTral nervous sysTem (CNS). This daTa demonsTraTes The possibiliTy of sTem cell Therapy in CNS and collecTively provide necessary foundaTion for overcoming challenges To The enhancemenT of TranslaTional regeneraTive medicine of brain and opTic nerve injury.

New Trends in RNA-Seq

来自Illumina China的测序产品经理余菽亮，分别从以下几个方面做了详细介绍： 在RNA序列的新的趋势，RNA序列的好处，RNA序列的挑战RNA序列的进化，TruSeq STanded RNA dUTP meThod ，提供完整的rRNA转录覆盖更多还原，TruSeq @ RNA库准备概述，单细胞测序的方法个别肿瘤细胞的转录组分析，细胞类型特异性基因表达标记，Fluidigm单细胞自准备系统概述等。

Novel signaling by The IKK complex

Signal TransducTion plays a pivoT role in regulaTing cell funcTions, from proliferaTion, differenTiaTion, programmed cell deaTh, and TransformaTion. DeregulaTion of signal TransducTion could lead To various human diseases even cancer. ExTracellular signals are TransmiTTed inTo cells via an inTracellular signaling neTwork ThaT is composed of mulTiple signaling paThways, dicTaTing cellular funcTions, such as growTh, differenTiaTion, programmed deaTh (apopTosis) and TransformaTion.
AlThough we have learnT a greaT deal abouT The archiTecTure of The inTracellular signaling neTwork, our undersTanding of iTs biology is limiTed. The work in my laboraTory focuses on elucidaTing molecular mechanisms underlying plasTiciTy and specificiTy of inTracellular signaling neTwork using c- Jun N-Terminal proTein kinase (JNK) and IkB kinase (IKK)/NF-kappaB as molecular probes and undersTanding The impacT of deregulaTing The inTracellular signaling neTwork on human diseases