AGENDA

 

Scheduler


April, 19
10:00 - 22:00 Registration, Pine City Hotel(青松城大酒店)
April, 20
08:30 - 08:45 Opening Ceremony
08:45 - 12:00 Session 1, Chemical biology of the epigenetic signals and players
Chairman: Yi Zhang and Guoliang Xu
08:45 - 09:10 DNA Oxidation towards Totipotency in Mammalian Development   ……Guoliang Xu (China)
09:10 - 09:35 Structure of a CENP-A-Histone H4 Heterodimer in Complex with Chaperone HJURP…… Ruiming Xu (China)
09:35-10:00 Functional assembly of CENP-S and CENP-X tetrameric complex is essential for accurate chromosome segregation in mitosis…… Xuebiao Yao (China)
10:00 - 10:20 Tea Break
10:20 - 10:45 Mechanism and function of Tet-mediated 5mC oxidation…… Yi Zhang (USA)
10:45 - 11:10 Metabolism regulation and human diseases …… Shimin Zhao(China)
11:10 - 11:35 Neuronal activity induced DNA modifications in the adult brain…… Hongjun Song (USA)
11:35 - 12:00 Biogenesis of PIWI-interacting RNAs and transposon slicing in Drosophila…… Haruhiko Siomi (Japan)
12:00 - 13:30 Lunch
   
13:30 - 17:10 Session 2,
Epigenomic Perspectives of the complex biological systems

Chairmen Hendrik G. Stunnenberg and Bin Ren
13:30 - 13:55 The Transcriptional and Epigenome Foundations of Ground State Pluripotency…… Hendrik G. Stunnenberg (Netherlands

13:55 - 14:20 Histone arginine methylation in cancer and differentiation…… Tapas K Kundu (India)
14:20 - 14:45 Analyses of Parent-of-origin and Sequence Dependent DNA Methylation in the Mouse Genome…… Bin Ren (USA)
14:45 - 15:10 Distinctive role of DNA methylation in the epigenetic regulation of disease associated genes…… Young-Joon Kim (Korea)
15:10 - 15:30 Tea Break

15:30 - 15:55 Polycomb H3K27me3 and DNA methylation repressive marks are redistributed in cancer in a genomic region dependant manner…… Susan J. Clark (Australia)

15:55 - 16:20 Genome-wide profile reveals an important role for H2B mono-ubiquitylation and hDot1L in transcription elongation of human cells……Daeyoup Lee (Korea)
16:20 - 16:45 Uniform, optimal framework for integrative analysis of chromatin profiles ……Shyam Prabhakar (Singapore)
16:45 - 17:10 Comparative epigenomics……Sheng Zhong  (USA)
17:10 - 18:40 Poster Session
April 21,
  Genome Medicine Workshop " Epigenetics in Diseases"

08:20 - 12:00 Session 3: Epigenetics in Cancer
  Chairmen Rebecca Furlong and Toshikazu Ushijima
08:20 - 08:45 Epigenetic disruption of cell signaling regulation in human cancers…… Qian Tao (Hong Kong)
08:45 - 09:10 Induction Mechanisms of Aberrant DNA Methylation……Toshikazu Ushijima (Japan)
09:10 - 09:35 Polycomb repressive complex 2-mediated epigenetic plasticity contributing to establishment of tissue heterogeneity in glioblastoma……Yutaka Kondo (Japan)
09:35 - 10:00 Chromatin Remodelers in Cancer……Bin-Tean The(Singapore)
10:00 - 10:20 Tea Break
10:20 - 10:45 DNA methylation cancer diagnostics Promises and Challenges……Jingde Zhu (China)
10:45 - 11:10 Deregulation of transcriptional and post-translational controls of DNA methyltransferases in lung cancer……Yi-Ching Wang (Tannan)

11:10 - 11:35 DNA methylation and demethylation in cancer development……Li-Jung Juan (Taipei)

11:35 - 12:00 DNA Methylation in Cell Differentiation and Transformation…… Tohru Nakano (Japan)
12:00 - 13:30 Lunch
   
13:30 - 17:10 Session 4,  Epigenetics in Other Diseases
   Chairmen: Isabelle Mansuy and Esteban Ballestar
13:30 - 13:55 Epigenetic modifiers in mammalian development and diseasess……Taiping Chen (USA)

13:55 - 14:20 Epigenomics of brains of patients with bipolar disorder and schizophrenia…… Kazuya Iwamoto (Japan)
14:20 - 14:45 Epigenetic Dysregulation in Immune System Models……Esteban Ballestar (Spain)
14:45 - 15:10 Sirtuin 1 in immune regulation and autoimmunity…… Deyu Fang (USA)
15:10 - 15:30 Tea Break
15:30 - 15:55 Epigenetics of Complex Behaviors and their Inheritance in Mammals…… Isabelle Mansuy (Switzerland)
15:55 - 16:20 Human Transgenerational Responses……Marcus E Pembrey (UK)
16:20 - 16:45 From fat flies to skinny mice: Genome-wide functional RNAi reveals distinct roles for developmental and chromatin-based regulation of obesity……J. Andrew Pospisilik (Germany)
16:45 - 17:10 Sensing gene-regulatory hyperglycemic changes vascular endothelial cells... Assam El-Osta (Australia)
17:10 - 18:40 Poster Session
April 22,
08:20 - 12:00 Session 5: The epigenetic(-omic) in complex biological systems (1)
  Chairman:     Howard Cedar and Hiroyuki Sasaki
08:20 - 08:45 Epigenetic Regulation of Aging…Jing-Dong Jackie Han (China)
09:10 - 09:35 Programming DNA Methylation During Development……Howard Cedar (Israel)
09:10 - 09:35 Identification of DNA methylation differences correlated with transcriptional divergence between humans and chimpanzees in chromosomes 21 and 22……Hiroyuki Sasaki (Japan)
09:35 - 10:00 A Role for Small RNAs in DNA Double-Strand Break Repair……Yijun Qi (China)
10:00 - 10:20 Tea Break
10:20 - 10:45
Epigenetic role of Additional Sex Comb-like (ASXL) family in nuclear hormone receptor signaling…. Soo-Jong Um (Korea)
10:45 - 11:10 Systematic analysis of defined factor reprogramming……Yuin-Han Jonathan Loh (Singapore)
11:10 - 11:35 3D Chromosomal Architectures and Transcriptional Regulation……Yijun Ruan (Singapore)

11:35 - 12:00 Genetic determinants of epigenetic repression…Dirk Schübeler (Switzerland)
12:00 - 13:30 Lunch

   
13:30 - 16:00 Session 6, The epigenetic(-omic) in complex biological systems (2)
  Chairmen:  Craig L. Peteron and Dirk Schübeler

13:30 - 13:55 Chromatin Dynamics and Genome Integrity…… Craig L. Peterson (USA)
13:55 - 14:20 The DNA methylome of the human placenta……Chunming Ding (Singapore)
14:20 - 14:45 Control of seed germination by posttranslational histone modificatio...... Yoo-Sun Noh ( Korea)

14:45 - 15:10 Interplay between genes and the environment via epigenetic mechanisms in neural stem cells...... Kinichi Nakashima (Japan)
15:10 - 15:35 The impact of early life experience on adult DNA methylation in the brain and in peripheral tissues.... Moshe Szyf (Canada)
15:35 - 16:00 Systems Biology of Stem Cells…… NG Huck Hui (Singapore)
16.00- Closing ceremony
 


Program details  


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