The Linux for Biotechnology project (LfB)致力于收集各种Linux系统环境下的生物技术相关软件，并提供方便的点击安装操作及相关文献等等。原始网站。
LFB计划的实施，使得生物学家可以用普通的PC机便可完成非常昂贵的服务器才能完成的工作。目前的LFB包括以下linux系统下的生物软件，资料加文献共计480M，解压后超过1G的内容，均加入到生物软件光盘4（biosoft4）中：

• abacus - Analysis of Blake's Conjecture Using Simulations
• ae2 - Sequence alignment editor
• alfresco - Comparitive sequence analysis
• artemis - DNA sequence viewer and annotation tool
• beta - Estimation of alpha - Nonparametric linkage analysis
• biomail - web-based application for medical researchers and biologists.
• bioperl - perl tools for Molecular biology
• biopython - Python tools for Molecular biology
• codonW- A package for codon usage analysis.
• DEODAS - DEgenerate Oligonucleotide Design & Analysis System
• Distutils - Python distribution tools
• DND - Protein molecular dynamics simulation/visualization
• DomainFinder - An interactive program for the determination and characterization of dynamical domains in proteins.
• dx - Data Explorer, visualisation package
• e-PCR - Sequence mapping by Electronic PRC
• EdIt - An automatic editor for DNA sequence data
• efetch - Retrieve entries from sequence databases
• EMBOSS - EMB Open Source Software
• ESPript - Creates postrcipt sequence renderings
• fastlink - Genetic linkage computations
• garlic - Molecular visualization
• GenoCheck - A method for detecting errors in pedigree data
• genpak - Utilities to manipulate DNA sequences
• gmaes - Evolution simulations
• gperiodic - Periodic table
• gibbs - Calculation of Probabilities for Diallelic Traits on Complex Pedigrees
• hmmer - Biological sequence analysis using profile hidden Markov models
• ImageJ - Java Image viewer
• jalview - a java multiple alignment editor
• jmol - an open-source molecule viewer and editor
• kmol - Molecular weight calculator
• ldb_2b - Hybrid mapping
• LEKSBOT - a botanical lexicon
• lintre - Phylogenetic tests of the molecular clock and linearized tree
• melting - nearest-neighbor computation of nucleic acid hybridation
• MIRA - DNA shotgun sequence data assembler
• mmlib - A C++ macromolecular class library
• mmtool - A macromolecular visualisation tool
• pdbtool - A macromolecular visualisation tool
• moldy - a general-purpose molecular dynamics simulation program
• ncbi-tools - NCBI Software Development Toolkit was developed for the production and distribution of GenBank, Entrez, BLAST, and related services by NCBI.
• Blastall - NHGRI Blastall (a perl interface)
• njbafd - Neighbor-joining tree construction from allele frequency data
• njbtie - search all tie neighbor-joining trees and UPGMA trees and for bootstrapping
• oligomap - OLIGOMAP is a tool to help researchers engineer restriction sites into oligonucleotides by silent mutagenesis
• orfind - orfind is a command line version of ORF Finder (http://www.ncbi.nlm.nih.gov/gorf/gorf.html)
• pdb2cif - convert PDB to CIF format
• pftools - pftools is a collection of experimental programs supporting the generalized profile format and search method of PROSITE and NUCSITE.
• pima - Pattern-Induced Multi-sequence Alignment program
• pseudoknots - An extension of the Zuker M FOLD algorithm to optimal minimum energy prediction of pseudoknotted RNA structures
• plato - Partial likelihoods expressed through optimisation
• primer3 - Primer3 picks primers for PCR reactions
• PSPP - Statistical analysis package.
• puzzle - Maximum likelihood analysis for nucleotide, amino acid, and two-state data
• PSeq-Gen - An application for the Monte Carlo simulation of protein sequence evolution along phylogenetic trees
• QDate - Estimates date of divergence using data for sequence parirs
• QuickPDB - Java Applet to view Protein Data Bank
• rhmapper - A package for creating radiation hybrid maps
• rnabob - searches for RNA motifs in sequence databases
• SampLin - Data Acquisition package
• sc_rate - Evaluates the quality of any sequence alignment.
• Topal - Package for Detecting Recombination Breakpoints
• RasMol2 - molecular graphics program intended for the visualisation of proteins, nucleic acids and small molecules.
• pasu - Probability and Statistics Utilities
• PVM - Parallel Virtual Machine
• PyMOL - molecular graphics program designed for rapid and efficient generation of high-quality molecular graphics animations.
• seals - System for Easy Analysis of Lots of Sequences
• sendbs - Average nucleotide diversity within and between populations
• sequin - Program to aid submission of sequences to GenBank, EMBL and DDJB
• seqsplit - Programs for running blastx on very long queries
• sibs - Sib Pair Analysis
• simPCR - check an sfind file from GCG for sequences that have homology to 2 opposite primers.
• sog - algorithm to find the most parsimoneous nucleotide phylogenetic tree
• TipDate - A program to estimate the rate of molecular evolution and time-scale of a phylogeny from dated sequences.
• tRNAscan - a program for improved detection of transfer RNA genes in genomic sequence
• treevolve - a program to simulate the evolution of DNA sequences under different population dynamic scenarios
• vanilla - command line programs (written in Java) to provide simple access to the functionality of PAL
• vaspview - scientific visualization package for examining output files generated by the Vienna Ab-initio Simulation Package
• w2h - WWW interface to the GCG Sequence Analysis Software Package
• wise - DNA and protein sequence comparison package

所有以上软件均在RedHat (v6.2) 和SuSE (version 6.4)下测试通过。

以上软件，除特别注明外，均在生物软件光盘4中。