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Adenovirus DIC video- Real-time differential interference contrast microscopy of neonatal rat cardiomyocytes showing the effect of altering tropomodulin expression upon myofibril organization and beating. .
Doxorubicin DIC video- Real-time differential interference contrast microscopy of neonatal rat cardiomyocytes showing the effect of doxorubicin upon upon myofibril organization and beating. .
 A normal cardiomyocyte labeled with antibodies to alpha-actinin (red) and tropomodulin (green) rotated + 30 degrees off axis from the X-Y plane of original viewing. The close packing and parallel alignment of myofibrils is clearly evident in this cell. .
 Another normal cardiomyocyte as described above. .
 A cardiomyocyte from a transgenic mouse showing accumulation of tropomodulin. This cell shows accumulation of tropomodulin reactivity which appears to accululate in patches along the length of the myofibrils. This cell is likely to have been in the process of myofibril degeneration. .
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