Naming mouse strains
There are internationally accepted rules to name transgenic and knock-out mice. See the following links:
Mouse Nomenclature Rules and Guidelines
These are suggestions about how to name mice, following the above quoted rules:
Transgenic mice:
promoter and gene combined acronymmutation - founder# - mouse#
example: lckB6 -16 -123
example: eµSVIRTA2tm -2 -65
Breeding of two transgenic strains will be:
promoter and gene combined acronymsmutation - mouse#
example: CD19Cre-CMVHAB6lox -8
The promoter and gene names may be combined in order to have a very short, but explicative 4-6 letter heading
Strain has been omitted, because most of the mice used are outbred. Inbred lines may be indicated after the founder with an i for inbred.
mice are numbered sequentially as they are born. A progressive numbering is used for each line. This will allow toe identification of mice, and an unique number for each mouse in the line.
Knock-out mice (Targeted mutations):
genemutation - ES cell clone - mouse#
example: B6D-T1/8-28
Transgenic and KO breeding:
KO nameTG acronymmutation - mouse#
example: p53null-lckB6 -123
example: B6D-MD4 -65
Individual mice will be reported as
Transgenics:
TG or TG/- or TG/TG when transgenics Knock-out:
+/+ or +/- or -/-
+/+, +/D and D/D
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