The "French paradox" is a term that refers to the apparent contradiction observed in European populations who consume high fat diets, yet enjoy a reduced mortality from coronary artery disease. This surprising fact has been attributed to the beneficial effects of red wine, which contains antioxidant compounds such as resveratrol, catechin, epicatechin and proanthocyanidins. Results from this laboratory study suggest that the polyphenolic compounds present in red wine also may confer protection against ischemic reperfusion injury (damage that occurs when blood flow is restored to the heart). These benefits are believed to be related to the peroxyl radical scavenging abilities of compounds such as resveratrol and proanthocyanidins.
Das D, Sato M, Ray P, et al. Cardioprotection of red wine: role of polyphenolic antioxidants. Drugs Exptl Clin Res 1999; 25(2/3): 115-120.
