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Cushing's syndrome
<endocrinology, syndrome> An increased
concentration of
glucocorticoid hormone (
ACTH) in the
bloodstream that is
being produced by an
adrenal gland tumour (
adenoma).
Ectopic Cushing
syndrome refers to the
production of ACTH in a location other than the
pituitary gland or
adrenal gland.
Examples of ectopic sites include thymoma, medullary carcinoma of the thyroid, pheochromocytoma, islet cell tumours of the pancreas and oat cell carcinoma of the lung.
Symptoms include weight gain, central obesity, moon face, weakness, fatigue, backache, headache, increased thirst, increased urination, impotence, mental status changes and muscle atrophy. Treatment varies with cause. If an ACTH secreting tumour is involved then it must be removed surgically.
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Cushing's disease,
Cushing's pituitary basophilism,
Cushing's sutureNext:
Cushing's syndrome medicamentosus,
cushing syndrome,
cushion
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