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Cooley's anaemia

<haematology> A genetic disease that results when there is a defect in the synthesis of one (or more) of the subunits of haemoglobin. The subunits are referred to as alpha or beta globin chains. As a result of a genetic defect red blood cells are small and hypochromic (low haemoglobin in the cell). Anaemia is common. Incidence is approximately 4 out of 100,000 individuals. Genetic testing is recommended in pregnant females of Mediterranean descent for the purpose of identifying carriers of this potentially serious genetic disease.

Origin: Gr. Haima = blood


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