基因功能与表达的经典文献汇集
生物谷2005-6-10注：因Science在2005年不再对中国免费使用，因此以下文章不能再下载了。如果您需要的话，请与我们联系，或升级为我们VIP会员，我们将免费替你们查询一定数量的文献。申请个人VIPGene FunctionModulation of Phospholipid Signaling by GLABRA2 in Root-Hair Pattern Formation Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis Role of Chloroplast Protein Kinase Stt7 in LHCII Phosphorylation and State Transition in Chlamydomonas Perspective: BOTANY: Genetic Control of Surface Curvature Perspective: BOTANY: Positional Cloning of the Human Quantitative Trait Locus Underlying Taste Sensitivity to Phenylthiocarbamide COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor Passage of Heme-Iron Across the Envelope of Staphylococcus aureus Role of a Highly Conserved Bacterial Protein in Outer Membrane Protein Assembly Single-Gene Greenbeard Effects in the Social Amoeba Dictyostelium discoideum Role of Melanopsin in Circadian Responses to Light Melanopsin (Opn4) Requirement for Normal Light-Induced Circadian Phase Shifting Viewpoint: An Overview of Insecticide Resistance Viewpoint: Plasmodium Chloroquine Resistance and the Search for a Replacement Antimalarial Drug Immunity-Related Genes and Gene Families in Anopheles gambiae Evolution of Supergene Families Associated with Insecticide Resistance Chloroquine Resistance in Plasmodium falciparum Malaria Parasites Conferred by pfcrt Mutations Genetic Loci Affecting Resistance to Human Malaria Parasites in a West African Mosquito Vector Population Perspective: GENETICS: Perspective: PARASITOLOGY: A Single P450 Allele Associated with Insecticide Resistance in Drosophila Perspective: EVOLUTIONARY GENETICS: hamlet, a Binary Genetic Switch Between Single- and Multiple- Dendrite Neuron Morphology The Calicheamicin Gene Cluster and Its Iterative Type I Enediyne PKS Role of Genotype in the Cycle of Violence in Maltreated Children News: PSYCHOLOGY: A Conserved p38 MAP Kinase Pathway in Caenorhabditis elegans Innate Immunity Regulation of Cerebral Cortical Size by Control of Cell Cycle Exit in Neural Precursors News: DEVELOPMENT: Serotonin Transporter Genetic Variation and the Response of the Human Amygdala News: NEUROSCIENCE: Multiple Roles of Arabidopsis VRN1 in Vernalization and Flowering Time Control Generation of Self-Incompatible Arabidopsis thaliana by Transfer of Two S Locus Genes from A. lyrata Induction of T Helper Type 2 Immunity by a Point Mutation in the LAT Adaptor A LAT Mutation That Inhibits T Cell Development Yet Induces Lymphoproliferation A Heat-Sensitive TRP Channel Expressed in Keratinocytes Premature Aging in Mice Deficient in DNA Repair and Transcription Perspective: AGING: Influence of Gene Action Across Different Time Scales on Behavior News: GENETICS: A MADS-Box Gene Necessary for Fruit Ripening at the Tomato Ripening-Inhibitor (Rin) Locus Perspective: PLANT BIOLOGY: Systemic RNAi in C. elegans Requires the Putative Transmembrane Protein SID-1 Living with Lethal PIP3 Levels: Viability of Flies Lacking PTEN Restored by a PH Domain Mutation in Akt/PKB Requirement of the Activation-Induced Deaminase (AID) Gene for Immunoglobulin Gene Conversion Perspective: IMMUNOLOGY: Immunoglobulin-Domain Proteins Required for Maintenance of Ventral Nerve Cord Organization News: NEUROSCIENCE: Unique and Redundant Connexin Contributions to Lens Development Identification of a Major Gene Regulating Complex Social Behavior Requirement of Math1 for Secretory Cell Lineage Commitment in the Mouse Intestine Perspective: DEVELOPMENT: Dynamic Disruptions in Nuclear Envelope Architecture and Integrity Induced by HIV-1 Vpr Perspective: VIROLOGY: Triallelic Inheritance in Bardet-Biedl Syndrome, a Mendelian Recessive Disorder Perspective: GENETICS: C. elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance Impairment of Mycobacterial But Not Viral Immunity by a Germline Human STAT1 Mutation Modulation of Cell Proliferation by Heterotrimeric G Protein in Arabidopsis G Protein Regulation of Ion Channels and Abscisic Acid Signaling in Arabidopsis Guard Cells Perspective: PLANT BIOLOGY: Spermiogenesis Deficiency in Mice Lacking the Trf2 Gene astray, a Zebrafish roundabout Homolog Required for Retinal Axon Guidance Molecular Mechanisms of the Biological Clock in Cultured Fibroblasts Perspective: CANCER: Sterility of Drosophila with Mutations in the Bloom Syndrome Gene -- Complementation by Ku70 Regulation of Vegetative Phase Change in Arabidopsis thaliana by Cyclophilin 40 Arabidopsis NPL1: A Phototropin Homolog Controlling the Chloroplast High-Light Avoidance Response Future Directions: Toward Behavioral Genomics Future Directions: Functional Annotation of Mouse Genome Sequences Human DNA Repair Genes SUB1, an Arabidopsis Ca2+-Binding Protein Involved in Cryptochrome and Phytochrome Coaction Broad-Spectrum Mildew Resistance in Arabidopsis thaliana Mediated by RPW8 
Extended Life-Span Conferred by Cotransporter Gene Mutations in Drosophila
News: AGING RESEARCH: Impaired Cued and Contextual Memory in NPAS2-Deficient Mice Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1 A Mutation in PRKAG3 Associated with Excess Glycogen Content in Pig Skeletal Muscle Eta-1 (Osteopontin): An Early Component of Type-1 (Cell-Mediated) Immunity Control of Circadian Rhythms and Photoperiodic Flowering by the Arabidopsis GIGANTEA Gene Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis 
Review: Nutritional Genomics: Manipulating Plant Micronutrients to Improve Human Health Review: Plant Functional Genomics BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator Arabidopsis Galactolipid Biosynthesis and Lipid Trafficking Mediated by DGD1 Math1: An Essential Gene for the Generation of Inner Ear Hair Cells SPA1, a WD-Repeat Protein Specific to Phytochrome A Signal Transduction The Pex16p Homolog SSE1 and Storage Organelle Formation in Arabidopsis Seeds Signaling of Cell Fate Decisions by CLAVATA3 in Arabidopsis Shoot Meristems News: PLANT BIOLOGY: Abnormal Spindle Protein, Asp, and the Integrity of Mitotic Centrosomal Microtubule Organizing Centers Role of Pitx1 Upstream of Tbx4 in Specification of Hindlimb Identity News: DEVELOPMENTAL BIOLOGY: Truncated RanGAP Encoded by the Segregation Distorter Locus of Drosophila 
Perspective: GENETICS:
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  Regulation of Gene ExpressionRegulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor Cooperation Between RNA Polymerase Molecules in Transcription Elongation Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies Perspective: MOLECULAR BIOLOGY: Requirement of Cks2 for the First Metaphase/Anaphase Transition of Mammalian Meiosis Accumulation of Phosphorylated Repressor for Gibberellin Signaling in an F-box Mutant Perspective: BOTANY: Brevia: Vertebrate MicroRNA Genes Paucity of Genes on the Drosophila X Chromosome Showing Male-Biased Expression Perspective: GENETICS: Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff Loci Perspective: TRANSCRIPTION: CREM-Dependent Transcription in Male Germ Cells Controlled by a Kinesin Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes A Kinetic Framework for a Mammalian RNA Polymerase in Vivo News: CELL BIOLOGY: Requirement of Hos2 Histone Deacetylase for Gene Activity in Yeast The I Perspective: SIGNAL TRANSDUCTION: Transcriptional Regulatory Networks in Saccharomyces cerevisiae Network Motifs: Simple Building Blocks of Complex Networks Oscillatory Expression of the bHLH Factor Hes1 Regulated by a Negative Feedback Loop Perspective: SYSTEMS BIOLOGY: Coordinate Regulation of Transcription and Splicing by Steroid Receptor Coregulators Separable Roles for rent1/hUpf1 in Altered Splicing and Decay of Nonsense Transcripts Perspective: RNA EVENTS: Instruction of Translating Ribosome by Nascent Peptide Perspective: BIOCHEMISTRY: Tissue-Specific Regulation of Retinal and Pituitary Precursor Cell Proliferation Stochastic Gene Expression in a Single Cell Perspective: GENETIC NETWORKS: White Collar-1, a Circadian Blue Light Photoreceptor, Binding to the frequency Promoter White Collar-1, a DNA Binding Transcription Factor and a Light Sensor Perspective: CIRCADIAN RHYTHMS: Alternatively Spliced TCR mRNA Induced by Disruption of Reading Frame Reversion of B Cell Commitment upon Loss of Pax5 Expression Regulation of Hypoxic Death in C. elegans by the Insulin/IGF Receptor Homolog Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones News: GENE TRANSCRIPTION: AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts Review: Emerging Roles of Ubiquitin in Transcription Regulation Genetic Dissection of Transcriptional Regulation in Budding Yeast Perspective: TRANSCRIPTION: Recruitment of a 19S Proteasome Subcomplex to an Activated Promoter Perspective: TRANSCRIPTION: The RAR1 Interactor SGT1, an Essential Component of R Gene-Triggered Disease Resistance Regulatory Role of SGT1 in Early R Gene-Mediated Plant Defenses Perspective: PLANT BIOLOGY: Regulation of Corepressor Function by Nuclear NADH Coordination of PIC Assembly and Chromatin Remodeling During Differentiation-Induced Gene Activation Perspective: TRANSCRIPTION: Review: Systems Biology: A Brief Overview Review: Reverse Engineering of Biological Complexity Review: A Genomic Regulatory Network for Development Review: Modeling the Heart--from Genes to Cells to the Whole Organ Review: Signal Transduction and the Control of Gene Expression Regulation of Organogenesis by the Caenorhabditis elegans FoxA Protein PHA-4 Modulation of NMDA Receptor-Dependent Calcium Influx and Gene Expression Through EphB Receptors Perspective: NEUROBIOLOGY: Stage-Specific Transcription of Distinct Repertoires of a Multigene Family During Plasmodium Life Cycle Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis Modulation of NMDA Receptor-Dependent Calcium Influx and Gene Expression Through EphB Receptors Perspective: BIOMEDICINE: Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo Perspective: STEM CELLS: Mammalian TOR: A Homeostatic ATP Sensor Requirement of Tissue-Selective TBP-Associated Factor TAFII105 in Ovarian Development Role of the Nonsense-Mediated Decay Factor hUpf3 in the Splicing-Dependent Exon-Exon Junction Complex Communication of the Position of Exon-Exon Junctions to the mRNA Surveillance Machinery by the Protein RNPS1 Regulation of Transcriptional Activation Domain Function by Ubiquitin Viewpoint: RNA: Guiding Gene Silencing Coordination of a Transcriptional Switch by HMGI(Y) Acetylation Perspective: GENE REGULATION: Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock A Transcriptively Active Complex of APP with Fe65 and Histone Acetyltransferase Tip60 Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation Control of a Genetic Regulatory Network by a Selector Gene Perspective: DEVELOPMENT: Regulation of Differentiation to the Infective Stage of the Protozoan Parasite Leishmania major by Tetrahydrobiopterin Review: NUCLEAR STRUCTURE: Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine DNA Replication-Independent Silencing in S. cerevisiae Establishment of Transcriptional Silencing in the Absence of DNA Replication Perspective: TRANSCRIPTION: Review: Insulators and Boundaries: Versatile Regulatory Elements in the Eukaryotic Genome Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus Orchestrated Transcription of Key Pathways in Arabidopsis by the Circadian Clock "Fluorescent Timer": Protein That Changes Color with Time News: CELL BIOLOGY: Allosteric Effects of Pit-1 DNA Sites on Long-Term Repression in Cell Type Specification News: CELL BIOLOGY: Transgene and Transposon Silencing in Chlamydomonas reinhardtii by a DEAH-Box RNA Helicase Perspective: MOLECULAR BIOLOGY: A Basal Transcription Factor That Activates or Represses Transcription Integration of Multiple Signals Through Cooperative Regulation of the N-WASP-Arp2/3 Complex Perspective: SIGNAL TRANSDUCTION: A Calmodulin-Related Protein That Suppresses Posttranscriptional Gene Silencing in Plants 
Ubiquitin-Activating/Conjugating Activity of TAFII250, a Mediator of Activation of Gene Expression in Drosophila Perspective: TRANSCRIPTION: A Link Between RNA Interference and Nonsense-Mediated Decay in Caenorhabditis elegans ORCA3, a Jasmonate-Responsive Transcriptional Regulator of Plant Primary and Secondary Metabolism Perspective: MOLECULAR BIOLOGY: Distinct Roles of CONSTANS Target Genes in Reproductive Development of Arabidopsis Perspective: PLANT BIOLOGY: Interacting Molecular Loops in the Mammalian Circadian Clock News: CIRCADIAN RHYTHMS: 
Direct Targeting of Light Signals to a Promoter Element-Bound Transcription Factor Perspective: PLANT BIOLOGY: Genetic Requirements for Inheritance of RNAi in C. elegans Perspective: MOLECULAR BIOLOGY: A Role for Nuclear Inositol 1,4,5-Trisphosphate Kinase in Transcriptional Control Perspective: SIGNAL TRANSDUCTION: Posttranscriptional Gene Silencing in Neurospora by a RecQ DNA Helicase A Pair of Related Genes with Antagonistic Roles in Mediating Flowering Signals Epigenetic Inheritance of Active Chromatin After Removal of the Main Transactivator Review: Epigenetics: Regulation Through Repression Coordinate Regulation of RAG1 and RAG2 by Cell Type-Specific DNA Elements 5' of RAG2 Genetic Mechanisms of Age Regulation of Human Blood Coagulation Factor IX Ploidy Regulation of Gene Expression Perspective: GENETICS: 
Review: Genetic Control of Branching Morphogenesis Regulation of Chamber-Specific Gene Expression in the Developing Heart by Irx4 Coordinated Regulation of Iron-Controlling Genes, H-Ferritin and IRP2, by c-MYC Silencing of Genes Flanking the P1 Plasmid Centromere RNAi in C. elegans: Soaking in the Genome Sequence CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV Independent and Epigenetic Regulation of the Interleukin-4 Alleles in CD4+ T Cells Functional Coherence of the Human Y Chromosome
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Global Gene ExpressionSelective Charging of tRNA Isoacceptors Explains Patterns of Codon Usage "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells A Stem Cell Molecular Signature Gene Expression During the Life Cycle of Drosophila melanogaster Allelic Variation in Human Gene Expression Single-Cell Gene Expression Profiling Homologies in Leaf Form Inferred from KNOXI Gene Expression During Development A Genomic-Systems Biology Map for Cardiovascular Function The Plasticity of Dendritic Cell Responses to Pathogens and Their Components Perspective: IMMUNOLOGY: A Phosphatase Associated with Metastasis of Colorectal Cancer Blazing Pathways Through Genetic Mountains A Gene Expression Map for Caenorhabditis elegans Patterns of Gene Expression During Drosophila Mesoderm Development Ordering Genes in a Flagella Pathway by Analysis of Expression Kinetics from Living Bacteria Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network The Human Transcriptome Map: Clustering of Highly Expressed Genes in Chromosomal Domains Global Analysis of the Genetic Network Controlling a Bacterial Cell Cycle Genomic Analysis of Gene Expression in C. elegans 
Genes Expressed in Human Tumor Endothelium News: TUMOR ANGIOGENESIS: The Genetic Program of Hematopoietic Stem Cells Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles Microarray Analysis of Drosophila Development During Metamorphosis Essay: AMERSHAM PHARMACIA BIOTECH & SCIENCE PRIZE: Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring Gene Expression Profile of Aging and Its Retardation by Caloric Restriction The Transcriptional Program in the Response of Human Fibroblasts to Serum News: MOLECULAR BIOLOGY: Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale |
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gorzata Lobocka,*, and Michael Yarmolinsky- 众说风云 (已有0条评论)
