Affinium Pharmaceuticals, Inc., (多伦多,Toronto)已开始执行由美国国防部(United States Department of Defense,DoD)所属单位降低防御威胁局(Defense Threat Reduction Agency,DTRA)所委托的一项美金 480万元额度的研究计划。
这项合约金主要是用于资助Affinium公司脂肪酸生合成抑制剂研究,以进行其数个潜力药物侯选分子的临床前动物实验。这些药物侯选分子己证明具有潜力,可用来治疗恐布份子生物战剂例如危险病原菌Francisella tularensis所造成的疾病。DTRA这项合约是以Affinium公司先前接受美国国家过敏与传染疾病研究所(National Institute of Allergy and Infectious Diseases)委托处理危险病原菌Francisella tularensis的研究成果为基础。http://www.afnm.com
英文原文:
Life Sciences News Brief
Vol.6 no.38 Jan. 17,2007
Affinium Pharmaceuticals, Inc., (Toronto) has executed a two-year US$4.8 million research contract with the Defense Threat Reduction Agency (DTRA), an agency of the United States Department of Defense (DoD). The contract will fund preclinical studies of selected compounds from Affinium's fatty acid biosynthesis inhibitor portfolio that have demonstrated potential as therapeutics for the treatment of diseases caused by serious pathogens including Francisella tularensis, a potential biological warfare and bioterrorism agent. This DTRA contract builds on Affinium's previous successful research into the inhibition of Francisella tularensis conducted with the US National Institute of Allergy and Infectious Diseases. http://www.afnm.com
