Neuron: 长时记忆形成的过程研究取得新进展

e all of the alleles in the genome for any complex quantitative trait in a single tube assay. These technologies will allow us to explore allelic contributions in complex mixed culture real environments and to investigate ecology at the genome level.

We are conducting a whole genome analysis (transcriptome and proteome) from blood of Human trauma patients. In this large clinical study we are establishing the standards for clinical genomics. We have developed 2 new technologies, "Molecular Inversion Probes" (MIP) for massive multiplex analysis of SNP and DNA content in Human and, "Mismatch Repair Detection" for discovery of rare Human polymorphisms. Both technologies are being applied to numerous clinical investigations.

Publications

· Elahi E, Khodadad A, Kupershmidt I, Ghasemi F, Alinasab B, Naghizadeh R, Eason RG, Amini M, Esmaili M, Esmaeili Dooki MR, Sanati MH, Davis RW, Ronaghi M, Thorstenson YR "A haplotype framework for cystic fibrosis mutations in iran." J Mol Diagn 2006; 8: 1: 119-27 More

· David L, Huber W, Granovskaia M, Toedling J, Palm CJ, Bofkin L, Jones T, Davis RW, Steinmetz LM "A high-resolution map of transcription in the yeast genome." Proc Natl Acad Sci U S A 2006; 103: 14: 5320-5 More

· Pierce SE, Fung EL, Jaramillo DF, Chu AM, Davis RW, Nislow C, Giaever G "A unique and universal molecular barcode array." Nat Methods 2006; 3: 8: 601-3 More

· Juneau K, Miranda M, Hillenmeyer ME, Nislow C, Davis RW "Introns regulate RNA and protein abundance in yeast." Genetics 2006; More

· Walton SP, Mindrinos MN, Davis RW "Analysis of hybridization on the molecular barcode GeneChip microarray." Biochem Biophys Res Commun 2006; 348: 2: 689-96 More

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