常用治疗斑秃方法基本无效
澳大利亚研究人员最近通过随机对照实验发现，现有常用治疗斑秃方法并不能有效促进毛发再生。
澳大利亚塔斯马尼亚大学的皮肤病专家迈克·斯拉登和同事在新一期医学电子期刊《循证医学数据库》（The Cochrane Library）上发表文章介绍说，他们通过17组随机对照实验对现有常用治疗斑秃方法的有效性进行评估，结果发现，没有一种疗法能长期帮助头发再生长，即只长出所掉头发的一半。研究人员说，之前很少有对治疗斑秃方法进行评估的随机对照实验。
斑秃是一种骤然发生的局限性斑片状的脱发性毛发病，俗称“鬼剃头”，是脱发中的一种。研究人员指出，当毛囊受到免疫系统攻击时就可能造成斑秃，同时身体和精神压力也可能导致斑秃。（来源：新华网）
生物谷推荐原始出处：
（The Cochrane Library），DOI: 10.1002/14651858.CD004413.pub2，FM Delamere, MM Sladden, HM Dobbins, J Leonardi-Bee
Interventions for alopecia areata
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Alopecia areata is a disorder in which there is loss of hair causing patches of baldness but with no scarring of the affected area. It can affect the entire scalp (alopecia totalis) or cause loss of all body hair (alopecia universalis). It is a relatively common condition affecting 0.15% of the population. Although in many cases it can be a self-limiting condition, nevertheless hair loss can often have a severe social and emotional impact.
To assess the effects of interventions used in the management of alopecia areata, alopecia totalis and alopecia universalis.
We searched the Cochrane Skin Group Specialised Register in February 2006, the Cochrane Central Register of Controlled Clinical Trials (The Cochrane Library Issue 1, 2006), MEDLINE (from 2003 to February 2006), EMBASE (from 2005 to February 2006), PsycINFO (from 1806 to February 2006), AMED (Allied and Complementary Medicine, from 1985 to February 2006), LILACS (Latin American and Caribbean Health Science Information database, from 1982 to February 2006), and reference lists of articles. We also searched online trials registries for ongoing trials.
Randomised controlled trials that evaluated the effectiveness of both topical and systemic interventions for alopecia areata, alopecia totalis, and alopecia universalis.
Two authors assessed trial quality and extracted the data. We contacted trial authors for more information. We collected adverse effects information from the included trials.
Seventeen trials were included with a total of 540 participants. Each trial included from 6 to 85 participants and they assessed a range of interventions that included topical and oral corticosteroids, topical ciclosporin, photodynamic therapy and topical minoxidil. Overall, none of the interventions showed significant treatment benefit in terms of hair growth when compared with placebo. We did not find any studies where the participants self-assessed their hair growth or quality of life.
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