2008-4-4 13:01:40

BJSM:太极和气功有助控制糖尿病

台湾和澳大利亚科研人员发现,每周打几小时太极拳,能显著改善Ⅱ型糖尿病的病症。

昆士兰大学的研究小组指出,其他形式的温和运动,也有助于控制糖尿病。但是“这些中国的运动形式比较容易学,而且不需要复杂或昂贵的设施”。

发表在《英国体育医学杂志》(British Journal of Sports Medicine)上的报告还说,虽然糖尿病和久坐不动的生活方式及肥胖有直接联系,但是太剧烈的运动也未必有好处。

在台湾的试验中,研究人员评估了30名Ⅱ型糖尿病人和30名同龄的健康人练习太极拳12个星期后,T辅助细胞(T-helper )的变化。他们发现糖尿病人的糖化血红蛋白 (HbAlc)显著降低,而且增强免疫反应的白细胞介素(interleukin)12水平倍增,T细胞的活力也明显增加了。

而澳大利亚的试验就发现,11名中老年人练习12周的气功和太极拳以后,血糖水平和“代谢综合征”都明显改善了。(来源:联合早报)

生物谷推荐原始出处:

(《英国体育医学杂志》(British Journal of Sports Medicine),doi:10.1136/bjsm.2007.043562,Shu-Hui Yeh, Kuender D Yang)

Regular Tai Chi Chuan exercise improves T cell helper function of type 2 DM patients with an increase in T-bet transcription factor and IL-12 production

Shu-Hui Yeh 1, Hau Chuang 2, Li-Wei Lin 3, Chiu-Yueh Hsiao 4, Pei-Wen Wang 5, Rue-Tsuan Liu 5 and Kuender D Yang 2*

1 Chang Gung Institute of Technology, Taiwan
2 Dept. Medical Research, Chang Gung Memorial Hospital at Kaohsiung,
Taiwan
3 College of Nursing, Deakin University, Burwood 3125, Australia, Australia
4 School of Nursing, Tzu-Hui Institute of Technology, Ping-Tung 926,
Taiwan, Taiwan
5 Division of Endocrinology & Metabolism, Chang Gung Memorial Hospital at Kaohsiung,
Taiwan

BACKGROUND-- Exercise has been shown to be beneficial in treatment of type 2 diabetes mellitus (DM); its benefit to immune function, however, remains to be determined.

OBJECTIVE-- This study investigated the effect of a 12-week course of Tai Chi Chuan (TCC) exercise on T cell helper (Th) reaction in type 2 DM patients.

DESIGH AND METHODS -- This study was a case-control design. Thirty pairs of type 2 DM patients and normal age-matched adults completed this study. Fasting blood glucose, HbA1c, mediators (IL-12, IL-4 and TGFfÒ) and transcription factors (T-bet, GATA-3 and FoxP3) of Th1/Th2/T regulatory (Treg) reaction were measured before and after a 12-week TCC exercise program. RESULTS -- Fasting glucose and HbA1c levels in the participating type 2 DM patients were significantly higher than age-matched controls before exercise. After the TCC exercise, HbA1c levels in type 2 DM patients significantly decreased (7.59 ¡&Oacute 0.32 vs. 7.16 ¡&Oacute 0.22 %; P= 0.047), along with a significant increase of blood IL-12 levels (5.96 ¡&Oacute 1.10 vs. 12.96 ¡&Oacute 3.07; P = 0.035). To probe molecular Th1/Th2/Treg reaction, we found that type 2 DM patients had lower T-bet, but not GATA-3 or FoxP3 expression than normal controls before TCC exercise. After the 12-week TCC exercise, T-bet expression significantly increased in type 2 DM patients.

CONCLUSIONS -- A 12-week TCC exercise program decreases HbA1c levels, along with increase of the Th1 reaction. A combination of TCC with medication may provide even better in both metabolism and immunity of type 2 DM patients.

(《英国体育医学杂志》(British Journal of Sports Medicine),doi:10.1136/bjsm.2007.045476,Liu Xin, Wendy

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