Optics Express：通过呼气诊断疾病的雷射分析器
据《世界日报》2月20日报道，美国科罗拉多大学科学家叶军领导下的研究人员，通过他们自行研究的“光腔直接光频梳光谱分析技术”，开发了一种新的雷射分析器。该仪器可以分析病人呼出的气体，帮助医生诊断出病人是否患癌症、肾脏病、气喘或其它病症。
《光学快报》（Optics Express）报告了该仪器的工作原理：该仪器利用镜子折射激光，可以检测到受测人呼出气体的每一个分子，从而分析出受测人的身体是否异常。（来源：科技部）
生物谷推荐原始出处：
（Optics Express），Vol. 16, Issue 4, pp. 2387-2397，Michael J. Thorpe, Jun Ye
Cavity-enhanced optical frequency comb spectroscopy: application to human breath analysis
Michael J. Thorpe, David Balslev-Clausen, Matthew S. Kirchner, and Jun Ye
Optics Express, Vol. 16, Issue 4, pp. 2387-2397
Keywords (OCIS):
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(140.4050) Lasers and laser optics : Mode-locked lasers
(300.1030) Spectroscopy : Absorption
Abstract
Broad-bandwidth, high-spectral-resolution optical detection of human breath has identified multiple important biomarkers correlated with specific diseases and metabolic processes. This optical-frequency-comb-based breath analysis system comes with excellent performance in all criteria: high detection sensitivity, ability to identify and distinguish a large number of analytes, and simultaneous, real-time information processing. We demonstrate a minimum detectable absorption of 8 x 10-10cm-1, a spectral resolution of 800 MHz, and 200 nm of spectral coverage from 1.5 to 1.7 μm where strong and unique molecular fingerprints exist for many biomarkers. We present a series of breath measurements including stable isotope ratios of CO2, breath concentrations of CO, and the presence of trace concentrations of NH3 in high concentrations of H2O.
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